William H. Miller III Department of Physics & Astronomy

Interphase Chromatin Undergoes a Local Sol-Gel Transition Upon Cell Differentiation Cell differentiation, the process by which stem cells become specialized cells, is associated with chromatin reorganization inside the cell nucleus. Here, we measure the chromatin distribution and dynamics in embryonic stem cells in vivo before and after differentiation. We find that undifferentiated chromatin is less compact, more […]

Emergence of size in living cells The emergence of macroscopic phenomena from interactions of its microscopic components is a problem permeating much of modern physics. Successes include our understanding of phase transitions, while turbulence still remains mostly mysterious. In cell biology, for more than a hundred years, it has been observed that micron-sized structures within […]